Researchers
Background:
I obtained my Bachelor Degree majoring in Bioengineering (2011) at China Pharmaceutical University (Nanjing, China). In the year of 2011-2014, I was studying neurobiology and got my Master degree at Peking University (Beijing, China). After that, I worked as a research manager at DAAN Gene Co., Ltd. Of Sun Yat-sen University for 8 months. As showing a great interest in CNS-related diseases and therapeutic targets, early in 2016, I was lucky to be a PhD student in cell biology at the Institute for Molecular Bioscience (UQ, Brisbane, Australia) with the supervision of Prof. David Fairlie and Dr. Abishek Iyer. My previous works focused on neuroprotection, neural development and signal pathways in cancer research.
Research interest:
Currently, I am pursuing my PhD degree in Prof. David Fairlie’s group at The University of Queensland. I am interested in exploring the relationship between
neuroinflammation and neurodegenerative disorders (mainly in AD). I am going to use novel compounds from our chemists, discovered from antiinflammatory and amyloid research programs, to penetrate the blood-brain barrier and regulate important physiological processes that become aberrant in neurodegenerative diseases.
Publications:
1. Huang H, Guo F, Cao Y, Shi W, Xia Q (2012). Neuroprotection by Manganese Superoxide Dismutase (MnSOD) Mimics: Antioxidant Effect and Oxidative Stress Regulation in Acute Experimental Stroke. CNS Neuroscience & Therapeutics, 18 (10): 811-818. IF=3.931
2. Cheng K*, Guo F*, Lu J, Cao Y, Xu H, Zhang B, Feng X, Xia Q (2015). MnTM-4-PyP Modulates Endogenous Antioxidant Responses and Protects Primary Cortical Neurons against Oxidative Stress. CNS Neuroscience & Therapeutics, 21(5):435-45.*equal contribution. IF=3.931
3. Jiaqi Lu*, Yuanzhao Cao*, Kuoyuan Cheng, Fei Guo, Xudong Feng, Qing Xia (2015). Berberine Regulates Neurite Outgrowth by Lowering Energy Status and Activating AMPK-related Pathways. Experimental Cell Research, 334(2):194-206. *equal contribution. IF=3.246
4. Jiaqi Lu*, Kuoyuan Cheng*, Yuanzhao Cao , Fei Guo, Bo Zhang, Huan Xu, Tianchang Wang, Qi Yang, Xudong Feng, Qing Xia (2015). New Mechanisms for Superoxide Scavenging Activity of Human Manganese Superoxide Dismutase (MnSOD) Determined by Lys68 Key Acetylation Site. Free Radical Biology & Medicine, 85:114-26. *equal contribution. IF=5.736
